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Pure Encapsulations Products (P-Q-R)
(All prices listed are Suggested Retail)
P5P
50 (activated B6)
60 caps - SRP$12.50 180 caps - SRP$31.40 The predominant form of circulating B6 Pyridoxal-5'-phosphate (P5P) is the active metabolite of pyridoxine and is the predominant form of plasma B6. P5P is required for proper absorption of B12 and magnesium, and for the production of gastric HCl. It is an important coenzyme in the metabolism of carbohydrates, fats, and proteins, and the elongation of essential fatty acids. It is required for the production of antibodies and red blood cells. P5P facilitates the release of glycogen (used in energy production) from the liver and muscles. In addition, P5P helps maintain the balance of sodium and potassium, which regulates body fluids and promotes the healthy functioning of the nervous and musculoskeletal systems. P5P 50 is beneficial to
a number of physiological functions, providing a wide range of nutritional support. each vegetable capsule contains:
2 capsules per day, in divided doses, with meals.
Pain Relieve
60 caps - SRP$18.70 120 caps - SRP$32.70 Support for reducing minor pain and maintaining a healthy inflammatory response Willow bark has a long history of traditional use for reducing minor pain. Several randomized human trials illustrate its ability to do so primarily through the actions of salicin, a source of salicylic acid. Additionally, it helps to maintain healthy prostaglandin metabolism and blood flow. Boswellia serrata has also revealed the potential to provide statistically significant support for reducing mild pain. AKBA, or 3-acetyl-11-keto-beta- boswellic acid, may be particularly supportive in maintaining healthy 5-lipoxygenase enzyme activity and leukotriene metabolism to maintain tissue comfort. Curcumin maintains healthy cyclooxygenase-2 enzyme activity while supporting healthy prostaglandin, leukotriene and thromboxane metabolism. Its ability to maintain a healthy inflammatory response has also been attributed to regulation of nitric oxide release. Devil's claw promotes both healthy cyclooxygenase-2 and 5-lipoxygenase enzyme activity. A review of 12 human studies indicates that devil's claw may reduce mild pain to promote musculoskeletal comfort and function. dl-Phenylalanine supports enkephalin activity, which impacts pain receptive neurons. This formula is designed to reduce minor pain and maintain a healthy inflammatory response by
supporting healthy enzyme and immune mediator activities. two vegetable capsules contain:
Warning: This product contains salicylates. Do not take if allergic to aspirin. Do not combine with aspirin or other products containing salicylates. Not to be used by pregnant or lactating women. Not to be used by children (ages 18 and under). Do not take with anticoagulant or antiplatelet drugs. Individuals with stomach problems or ulcers should consult their physician before using this product.
Premium formula, provides 15% ginsenosides *Panax ginseng has long been utilized to assist the body in adapting to physical and emotional stress. During prolonged exercise, Panax ginseng promotes endurance and stamina by sparing carbohydrates and allowing skeletal muscle to oxidize free fatty acids for energy production. Panax ginseng also encourages adrenal gland health in times of stress by maintaining healthy levels of certain adrenal hormones, most notably, corticosterone. This versatile herb supports male reproductive health by supporting testosterone and spermatozoa levels. In addition, Panax ginseng promotes memory and learning, and nutritionally supports immune function and cardiovascular health. Panax ginseng helps the body adapt to its environment by enhancing endurance and adrenal gland health. Pure Encapsulations Panax Ginseng provides 15% ginsenosides, the highest standardization available. Supplement Facts 2–3 capsules per day, in divided doses, between meals. each vegetable capsule contains:
Pancreatic Enzyme Formula
60 caps - SRP$20.80 180 caps - SRP$51.90 Natural digestive support This formula is designed to aid the body's natural digestive process. It provides a highly concentrated form of enzymes naturally secreted by the pancreas which are essential to the digestion of food and absorption of nutrients. The formula contains lipase, which digests fat; proteases, which digest protein; and amylases, which digest starch. Pancreatic Enzyme Formula provides a natural way to nutritionally
support proper digestive function. each vegetable capsule contains:
1–2 capsules with each meal.
Pancreatic VegEnzymes
L
60 caps - SRP$17.30 180 caps - SRP$33.30 Vegetarian pancreatic enzyme alternative with enhanced fat digestion support This enzyme blend provides a broad acting formulation derived from the plant sources Aspergillus oryzae and Aspergillus niger. It is a vegetarian alternative to Pancreatic Enzyme Formula for carbohydrate, lipid and protein digestion. These enzymes have several unique properties that enhance their ability to promote the optimal breakdown of foods and nutrients, including broad substrate specificity. This means that these enzymes have the ability to recognize and help digest a large number of target molecules. Plant enzymes are also active in a wide pH range, from about 3.5-8.5, indicating that their actions begin in the stomach and continue in the small intestine, promoting complete digestion. Pure Encapsulations Pancreatic VegEnzymes is comparable in amylase, protease and lipase profile to Pancreatic Enzyme Formula. Each 200 mg capsule
of Pancreatic VegEnzymes provides the equivalent of one 500 mg capsule of Pure Encapsulations Pancreatic Enzyme Formula. each
vegetable capsule contains:
1–2 capsules with each meal.
Pantethine
60 caps - SRP$33.90 120 caps - SRP$59.70 Lipid metabolism support *Pantethine is the active form of the B vitamin pantothenic acid and is a major component of coenzyme A, or CoA. In cells, CoA is essential for fatty acid transport and fatty acid metabolism. Several human studies demonstrate the ability of pantethine to maintain healthy utilization and metabolism of various lipids, promoting healthy cardiovascular function. Pantethine supports healthy triglyceride
and lipid metabolism. each vegetable capsule contains:
2–4 capsules per day, in divided doses, with meals.
Pantethine/Policosanol
60 caps - SRP$46.70 120 caps - SRP$81.40 Triglyceride and lipid metabolism support Pantethine is a variation of pantothenic acid that has demonstrated the potential to support lipid metabolism and to maintain healthy triglyceride levels. In a 16-week trial, pantethine supplementation supported healthy lipid balance in perimenopausal women. A 9-month study involving 16 subjects, a 3-month trial involving 12 male volunteers, and an 8-week, double blind investigation including 29 participants revealed the positive influence of pantethine on healthy triglyceride support. Policosanol is a well-tolerated mixture of long-chain aliphatic alcohols derived from sugar cane wax, promoting healthy lipid and triglyceride metabolism, platelet function, and antioxidant protection for cardiovascular health. Over a decade of short-term and long-term clinical research involving thousands of subjects reveals the safety and tolerability of policosanol. The enhanced triglyceride support potential of pantethine
is coupled with policosanol's lipid support properties to provide complementary support for promoting healthy cardiovascular
function. each vegetable capsule contains:
2–4 capsules per day, in divided doses, with meals.
Pantothenic Acid 120 VCaps - SRP $15.30
D-isomer pantothenic acid for cellular energy Pantothenic acid is a precursor of coenzyme A (CoA), an important cofactor and acyl group carrier in cells. One of the main functions for CoA is the formation of acetyl-CoA, vital for cellular respiration and the metabolism of carbohydrates and fatty acids through the Krebs cycle. Distribution studies indicate that tissues with the highest retention of pantothenic acid are the kidneys, pituitary gland, heart, muscle, liver and adrenal glands. Additionally, pantothenic acid is required for the synthesis of fatty acids and membrane phospholipids, the amino acids leucine, arginine and methionine, and isoprenoid derivatives, including steroid hormones, vitamin A and vitamin D. Pantothenic acid supports cellular energy production, adrenal and cardiovascular health, and synthesis of vitamins, amino acids, fatty acids, and steroid hormones Supplement Facts 1 capsule per day, with a meal.
PediaNutrients™ 120 VCaps - SR $13.10 Children's multi-vitamin/mineral formula for optimal health PediaNutrients™ is a hypo-allergenic, highly bioavailable multi-vitamin and multi- mineral formula specially formulated to help meet the daily nutrient needs of children. This gentle and easily assimilated formula provides the key vitamins and minerals that help support healthy growth and development in the doses that are consistent with the accepted scientific recommendations for children between the ages of 4 and 11. This formula is available in small capsules for easy swallowing and in a light tasting, natural strawberry banana flavored powder that is perfect for mixing in your child's favorite juice, milk or yogurt. PediaNutrients™ provides broad spectrum, scientifically based vitamin and mineral support
for young metabolic systems. four
vegetable capsules contain:
WARNING: Accidental overdose of iron-containing products is a leading cause of fatal
poisoning in children under 6. Keep this product out of the reach of children. In case of accidental overdose, call a doctor
or poison control center immediately.
*Zinc-carnosine complex for gastric health and comfort This patented, 1:1 chelate of zinc and l-carnosine provides a unique configuration that is important to this compound's activity. Zinc-carnosine has a slow disassociation rate and adheres to the stomach lining, allowing for prolonged protection. Once dissociated, zinc and carnosine provide synergistic antioxidant protection, strengthen the stomach's mucosal defenses, buffer gastric acid and maintain healthy cytokine release. Studies have suggested that this combination has greater effects on the integrity of the gastric lining than either ingredient alone. One Japanese multi-center, double-blind study involving 299 subjects described a positive effect of zinc-carnosine on objective and subjective parameters of normal gastric health and repair functions, especially after 8 weeks. Seven additional clinical evaluations with more than 550 volunteers indicate similar results. In recent in vitro and in vivo studies, zinc-carnosine stimulated healthy gut repair by supporting healthy colon cell reproduction and maintaining healthy villus function. In a double blind, randomized, cross-over trial, zinc-carnosine maintained healthy gut permeability. Extensively studied and utilized in Japan, this zinc-carnosine combination has an excellent safety profile. U.S. Patent 4,981,846. Peptic-Care ZC provides patented support for strengthening the stomach's mucosal defenses, buffering gastric acid, maintaining gastric integrity and providing antioxidant support for overall gastric health and comfort. Supplement
Facts 1–2 capsules per day, in divided doses, with meals. each
vegetable capsules contains:
Not to be taken by pregnant of lactating women.
Petadolex® 50 soft gels - SRP $55.70 Supports healthy cranial blood vessel function, may maintain proper histamine release Butterbur is a perennial shrub with a 2,000-year history of traditional use. In the last twenty-five years, it has been trusted extensively throughout Europe by neurologists and other health professionals. Petadolex®, a patented form of butterbur extracted from the root and standardized to contain a minimum of 15% petasin and isopetasin, has been studied for healthy cranial vessel support. Petasin-containing extracts of butterbur may also help to maintain healthy histamine and cytokine release. In one clinical trial with 60 participants, Petadolex showed the potential to support cranial vessel comfort and was well tolerated. After a twelve-week period, almost eighty percent of participants supplementing with Petadolex indicated a supportive effect. In part, the mechanism for this action may involve a supportive spasmolytic effect on smooth muscle in cranial blood vessels. A second study with 229 individuals indicated similar positive results. In this trial, optimal dosing of Petadolex provided significant support compared to placebo within one month. After three months, over seventy percent of individuals experienced a positive outcome. A petasin-containing butterbur leaf extract has been shown to maintain healthy histamine and cytokine release without sedative effects. In two clinical trials, butterbur maintained healthy nasal histamine release and leukotriene activity, supporting both subjective and objective parameters. Petadolex is standardized to contain at least 7.5 mg petasins per 50 mg and is processed to remove pyrrolizidine alkaloids. Petadolex® provides high capacity support
for healthy cranial blood vessel function. Butterbur may also promote immune function by maintaining healthy histamine and
cytokine release. each softgel capsule contains:
2–3 capsules per day, in divided
doses, with meals.
Phosphatidylcholine
60 caps - SRP$12.60 120 caps - SRP$31.40 Support for hepatic, cognitive and cellular health *Phosphatidylcholine, or PC, is an integral component of cell membranes and, as a source of choline, is also a precursor of the neurotransmitter acetylcholine. It also plays a role in liver health. In a multi-center, randomized, double blind, placebo-controlled trial conducted in Germany, investigators reported that PC helped support liver health by promoting healthy enzyme activity. Animal studies also report that soybean PC may promote healthy lipid metabolism at the hepato-billiary level. Additional animal studies indicate that PC promotes healthy liver and pancreatic antioxidant activity. PC has also been studied in the context of cognitive support and moderating stress. A long-term double-blind placebo controlled trial suggested that high dose soy lecithin containing phosphatidylcholine may lessen mild memory loss associated with aging. Pure Encapsulations concentrated soy-derived Phosphatidylcholine provides integral hepatic, cognitive,
and cellular health support. each softgel capsule contains:
each softgel capsule contains:
2–8 capsules daily in divided doses with meals.
Phyto-ADR
60 caps - SRP$16.70 120 caps - SRP$41.90 Vegetarian adrenal support formula This vegetarian formula provides wide range herbal and nutritional support for the adrenal glands. Panax ginseng and Eleutherococcus senticosus, or eleuthero, are highly recognized adaptogens, promoting physiological balance and resistance to stress. In part, they help to moderate the production of adrenocorticotrophic hormone (ACTH) and ultimately corticosterone activity. Corticosterone promotes the conversion of amino acids into carbohydrates and glycogen by the liver and stimulates glycogen formation in the tissues, supporting optimal energy reserves. Rhodiola rosea, containing rosavins and salidrosides, also acts to balance hypothalamic- pituitary-adrenal activity. Rhodiola can have a calming effect on the central nervous and supports healthy thyroid, thymus, and adrenal gland function. In particular, rhodiola may moderate the effects of physical and emotional stress. Recently, a double blind cross-over study suggests that rhodiola may help to moderate fatigue under stressful conditions. Astragalus and ashwagandha promote immune support and complement the adaptogenic activity of this formula. Calcium pantothenate, a vitamin B5 derivative, is essential for activating the adrenals. Collectively, these ingredients support the health and activity of the adrenal glands. Phyto-ADR
provides comprehensive support for healthy adrenal function. each vegetable capsule contains:
Not to be taken by pregnant or
lactating women
PhytoBalance
60 caps - SRP$17.60 120 caps - SRP$30.70 Promotes healthy estrogen and progesterone activity; reduces hot flashes This standardized herbal extract formula provides multifaceted support for the body during the hormonal changes that occur during menopause. PhytoBalance contains phytoestrogens, natural substances in plants that bind to estrogen receptor sites and exhibit weak estrogen-like activity. This formula also contains herbs with uterotonic properties. Finally, some of the ingredients in this formula may maintain healthy prolactin secretion. PhytoBalance naturally promotes estrogen-like activity and provides optimum support during periods of hormonal changes. each vegetable capsule contains:
Not to be taken by pregnant
or lactating women.
Policosanol
10mg - 60 caps - SRP$17.90 10mg - 120 caps - SRP$31.50 20mg - 60 caps - SRP$29.90 20mg - 120 caps - SRP$52.50 Supports healthy lipid metabolism in some individuals Policosanol is a mixture of long-chain aliphatic alcohols that naturally occur in sugar cane. Over a decade of short-term and long-term clinical research involving thousands of subjects reveals the safety and tolerability of policosanol. The promising results of randomized, double-blind placebo-controlled trials, including comparative studies, suggest that policosanol supports cardiovascular health. Though the mechanism for cardiovascular support of this substance remains unclear, policosanol may act in part by providing antioxidant protection, promoting healthy platelet function, and supporting healthy lipid metabolism. At the highest dosage recommended by Pure Encapsulations, policosanol may support healthy triglyceride metabolism in some individuals. Policosanol is a well-tolerated mixture of long-chain aliphatic alcohols derived from sugar cane wax, promoting healthy lipid metabolism, platelet function, and antioxidant protection for healthy cardiovascular function. each vegetable capsule contains:
1–2 capsules daily, in divided doses, with meals
Polyphenol Nutrients
180 caps - SRP$38.90 360 caps - SRP$69.90 Powerful polyphenol-rich multivitamin and multimineral formula with additional protection factors Packed with flavonoids and phenolic compounds from a unique blend of olive fruit, grape seed, pomegranate, green tea, quercetin and blueberry, this formula offers powerful overall cellular protection. It also contains the protective nutrients alpha lipoic acid, NAC, inositol and choline to complement the neural, cognitive, cardiovascular, liver and skin health properties of this diverse profile. Furthermore, Polyphenol Nutrients provides the advanced mineral delivery systems and active vitamin cofactors found in Nutrient 950® and UltraNutrient® for optimal bioavailability and utilization. As part of a well-balanced diet that is low in saturated fat and cholesterol, folic acid, vitamin B6 and vitamin B12 may reduce the risk of vascular disease.† †FDA evaluated the above claim and found that while it is known that diets low in saturated fats and cholesterol reduce the risk of heart disease and other vascular diseases, the evidence in support of the above claim is inconclusive. six vegetable capsules contain:
4–6 capsules per day, in divided doses, with meals.
Pomegranate Plus
(formerly PomEllagic™ Plus) 60 caps - SRP$22.70 120 caps - SRP$39.70 The combined nutritional power of pomegranate, açai and red raspberry for diverse antioxidant protection Polyphenols and anthocyanins are just some of the components of pomegranate responsible for its antioxidant properties, contributing to its potential to protect healthy vascular endothelial cells. Red raspberry flavonoids provide complementary vascular support, especially by neutralizing free radicals that attack lipid cell membranes. Ellagic acid, found in both extracts, also has a promising role in supporting liver, lung, esophagus, stomach, colon and prostate health. The prized palm berry açai of Brazil, where it is known as "the fruit of life", is a dynamic, nutrient dense addition to this formulation, offering anthocyanins, vitamins, minerals, amino acids, and essential fatty acids. In fact, the ratio of oleic, mono unsaturated and polyundaturated fatty acids in açai are comparable to that of olive oil. Naturally occurring alpha tocopherol and tocotrienols are also valuable components for lipid antioxidant protection. In a university study, açai berry also revealed important support for maintaining healthy cell cycle function. Pomegranate Plus provides a diverse profile of highly bioactive phytochemical, phenolic, flavonoid and nutritional components for exceptional vascular and cellular support potential. each vegetable capsule contains:
1–2 capsules per day, in divided
doses, with or between meals.
Potassium (aspartate)
90 caps - SRP$10.40 Essential to cardiovascular function Potassium activates many enzymatic reactions and is essential to a number of physiologic processes, including transmission of nerve impulses; contraction of cardiac, smooth, and skeletal muscles; gastric secretion; renal function; tissue synthesis; and carbohydrate metabolism. Potassium is the major cation of intracellular fluid and is essential for maintenance of acid-alkaline balance, isotonicity, and electrodynamic characteristics of the cell. In addition, it works with sodium to maintain healthy water balance, heart rhythm, and nerve and muscle function. Potassium is an essential mineral that offers a wide range of nutritional support to ensure healthy physiological functioning of diverse organ systems. each vegetable capsule contains:
2 capsules per day, in divided doses, with meals.
Potassium (citrate) 90 caps - SRP $11.10 180 caps - SRP $19.40 Essential to cardiovascular function Potassium activates many enzymatic reactions and is essential to a number of physiologic processes, including transmission of nerve impulses; contraction of cardiac, smooth, and skeletal muscles; gastric secretion; renal function; tissue synthesis; and carbohydrate metabolism. Potassium is the major cation of intracellular fluid and is essential for maintenance of acid-alkaline balance, isotonicity, and electrodynamic characteristics of the cell. In addition, it works with sodium to regulate water balance, heart rhythm, and normal nerve and muscle function. Potassium is an essential mineral that offers a wide range of nutritional support to ensure proper physiological functioning of diverse organ systems. each vegetable capsule contains:
2 capsules per day, in divided doses,
with meals.
Potassium Magnesium (aspartate)
90 caps - SRP$11.80 180 caps - SRP$20.50 Supports a number of physiologic functions, including cardiovascular health and muscle function Potassium and magnesium are essential for healthy nerve impulse function, muscle contraction, cardiovascular function, acid/alkaline balance and carbohydrate and nutrient metabolism. Magnesium also plays an important role in facilitating potassium utilization, helping to provide optimal support from this important combination. Potassium and magnesium provide key roles in heart, muscular, and nerve health. each vegetable capsule contains:
1–4 capsules per day, in divided doses, with meals.
Potassium Magnesium (citrate)
90 caps - SRP$11.80 180 caps - SRP$20.50 Supports a number of physiologic functions, including cardiovascular health and muscle function Potassium and magnesium are essential for healthy nerve impulse function, muscle contraction, cardiovascular function, acid/alkaline balance and carbohydrate and nutrient metabolism. Magnesium also plays an important role in facilitating potassium utilization, helping to provide optimal support from this important combination. Potassium and magnesium provide key roles in heart, muscular, and nerve health. each vegetable capsule contains:
2 capsules per day, in divided doses, with meals.
Pregnenolone
10mg - 60 caps - SRP$9.40 10mg - 180 caps - SRP$22.70 30mg - 60 caps - SRP$13.10 30mg - 180 caps - SRP$31.10 Natural precursor to over 150 steroid hormones Pregnenolone, 3-alpha-hydroxy-5-beta-pregnen-20-one, is a natural steroid hormone produced in the body from cholesterol. It has been described as the “Grandmother of all Steroid Hormones,” since all steroid hormones, over 150 of them, are derived from pregnenolone. Pregnenolone has been linked with positive support of the immune system, mood and memory. In the body, it takes one or two metabolic pathways, converting to DHEA and/or progesterone. It is likely that the body will convert pregnenolone appropriately, according to its needs. Studies show that the body makes 60% less of this hormone at age 75 than it does at age 35. Pregnenolone, a natural precursor to over 150 steroid hormones, helps support the immune system, mood and memory. each vegetable capsule contains:
Not to be taken by pregnant or lactating women.
Nutritional support for pregnancy and lactation *PreNatal Nutrients is a hypo-allergenic, highly bioavailable multi-vitamin and multi- mineral formula. It provides the core nutrients needed to help support maternal and fetal health in the doses that are consistent with the accepted scientific recommendations for pregnant and lactating women. Furthermore, PreNatal Nutrients provides 1 mg of folic acid for healthy neural and cellular development of the fetal brain and spinal cord, helping to prevent neural tube defects.† Pure Encapsulations PreNatal Nutrients provides broad spectrum vitamin and mineral support, including 1 mg folic
acid, for pregnant and lactating women. †Women who consume healthful diets with adequate folate may reduce their risk of having a child with birth defects of the brain or spinal cord. Folate intake should not exceed 250% of the DV (1,000 mcg). Supplement Facts 2 capsules per day, in divided doses, with meals. two vegetable capsules contain:
WARNING: Accidental overdose of iron-containing products is a leading cause of
fatal poisoning in children under 6. Keep this product out of the reach of children. In case of accidental overdose, call
a doctor or poison control center immediately.
ProBasics
563 g - French Vanilla - SRP $41.80 545g - Strawberry Banana Creme - SRP $41.80 603 g - Chocolate - SRP $42.80 Multi-supportive whey and rice protein beverage. Whey protein contains a superior profile of essential and nonessential amino acids and is particularly rich in tryptophan and the branched-chain amino acids (BCAA). Since the proportions of the essential amino acids in whey closely complement the specific requirements of human metabolism, whey protein is known for its high biological value (BV) and protein efficiency ratio (PER), which exceed most other animal and plant proteins in the diet. The whey protein in ProBasics is derived from U.S. herds. An advanced microfiltration process minimizes residual fat, cholesterol, and lactose while retaining key functional components such as lactoferrin, immunoglobulins, and glycomacropeptides. Lactoferrin and immunoglobulins play important roles in immune support. Whey protein is also a useful addition to weight management programs. Tryptophan is a natural precursor to serotonin, a neurotransmitter involved in the regulation of endocrine and brain activity responsible for regulation of emotion and appetite. Rice protein enhances the overall amino acid profile of this formula. As part of a balanced diet, ProBasics can be used as a daily wellness beverage for healthy protein nutrition. It can be taken with or between meals to support daily wellness, weight management, exercise nutrition or immune support. ProBasics delivers 31 grams of high quality protein per serving and is a source of tryptophan, BCAA, and other functional amino acids. It is easily digested, low in fat, naturally flavored, free of added sugar and contains less than 1% lactose. Its digestibility, amino acid profile, functional immune support proteins, easy preparation and French Vanilla, Strawberry Banana Creme and Chocolate flavors make it the protein supplement of choice. 1.5 scoops contain:
WARNING: Very low calorie protein diets (below 400 calories per day) may cause serious illness or death. Do not use
for weight reduction in such diets without medical supervision. Not for use by infants, children, pregnant or nursing women.
Notice: Use this product as a food supplement only.
Supplement Facts two scoops (1 g) contain:
This formula requires refrigeration to maintain culture viability.
A dairy-free blend of key probiotic bacteria to support immune and gastrointestinal health *This dairy–free formula provides 10 billion CFU of the beneficial bacteria Lactobacillus acidophilus, Lactobacillus rhamnosus, Bifidobacterium longum, Bifidobacterium bifidum and Bifidobacterium lactis. Research indicates that these strains may have particular health promoting properties for gastrointestinal (GI) and immune health. L. acidophilus and B. longum have been shown to promote healthy cytokine production in the colon and maintain healthy GI barrier function, in part by supporting the mucosal lining of the GI tract. Several trials have also revealed that mixed probiotic supplementation helps maintain intestinal flora, support healthy yeast balance, and promote GI comfort. A study involving elderly individuals indicated that a mixture of lactobacilli and bifidobacteria maintained healthy gut ecology. Studies also suggest that probiotics support immune health, enhancing B cell, T cell and NK cell function. A randomized, double blind, placebo–controlled intervention study involving 479 adults indicates that B. longum and B. bifidum promote overall health and T cell function. Another randomized, double blind, placebo–controlled clinical trial involving 25 elderly volunteers suggests that B. lactis encourages immune function by enhancing phagocytic capacity and activity. Probiotic–5 (dairy–free) is a high–strength blend of lactobacilli and bifidobacteria to promote GI tract health and comfort, immune cell function and overall health. Supplement Facts 1–2 capsules per day, in divided doses, with or
between meals. each vegetable capsule
contains:
This formula requires refrigeration to maintain culture viability.
Shelf-stable probiotic blend to support a healthy inflammatory balance within the GI tract* Probiotic G.I. provides 10 billion CFU per capsule of the beneficial bacteria Lactobacillus acidophilus, Lactobacillus salivarius, Lactobacillus casei, Bifidobacterium bifidum, Bifidobacterium lactis and Streptococcus thermophilus. Research indicates that these stains provide particular support for a healthy inflammatory balance within the GI tract. Beneficial microflora are crucial for proper gut associated lymphoid tissue (GALT) function and development. The GALT helps protect intestinal mucosa from allergens and toxins and is a major component of the body’s immune system. It is estimated that more than 70% of the body’s B lymphocytes are found in the GALT. Probiotics are believed to support healthy GALT composition, and in turn, support barrier function, GI epithelial cell health and T cell function within the GI tract. Some probiotic strains may also modulate local production of cytokines in the GI epithelium. L. casei and B. lactis support healthy T cell activity and cytokine production in the intestine, at least in part by regulating transcription of genes that encode for cytokines. L. acidophilus promotes healthy cytokine production in the colon. Research also suggests that metabolites produced from Streptococcus thermophilus may cross the intestinal barrier to support healthy cytokine production and inflammatory balance. Probiotic G.I. is designed to promote gut associated lymphoid tissue composition and function, supporting healthy barrier function, gastrointestinal cell health and inflammatory balance in the GI tract. Supplement Facts 1–2 capsules per day, in divided doses, with or between meals.
ProSoothe®
60 caps - SRP$23.00 120 caps - SRP$40.40 Menstrual comfort and support: supports mood, cramps and edema associated with the menstrual cycle ProSoothe® contains standardized herbal extracts which have been used for many years to support women's bodies during the menstrual cycle. These herbs act in various ways to respond to hormonal changes which occur in the monthly cycle; namely, they have been shown to maintain a healthy estrogen to progesterone ratio, in favor of progesterone, and to maintain healthy prolactin secretion. ProSoothe also supports prostaglandin metabolism and promotes a uterine-relaxant effect, thereby promoting menstrual comfort. ProSoothe® combines herbs that soothe the uterine muscle and normalize hormonal changes, which occur during the menstrual cycle. each vegetable capsule contains:
2–4 capsules per day, in divided doses, between meals. Use only during luteal phase of menstrual
cycle; i.e., in a typical 28 day cycle, begin on day 14 and take through 1st day of flow. Stop. Begin again on day 14.
ProstaFlo
90 caps - SRP$28.60 180 caps - SRP$50.00 Swedish flower pollen extract (hypo-allergenic) First developed in Sweden and used for over forty years in numerous countries, flower pollen extract contains a highly concentrated, 20:1 combination of water soluble to fat soluble flower pollen extracts (the allergenic outer husk is removed) from corn, timothy and rye. The fat-soluble constituents of this extract promote healthy leukotriene and prostaglandin production in vitro. An animal study indicates that the water-soluble fraction plays a synergistic role in maintaining healthy urethra smooth muscle function. A multiple-center, double blind study and a separate clinical evaluation of long-term consumption indicated that flower pollen extract supported healthy urinary function and prostate health in volunteers. Flower pollen extract contained in ProstaFlo offers concentrated support for urinary and prostate health. each vegetable capsule contains:
3–5 capsules per day, in divided doses, with meals.
PS 100 (standardized phosphatidylserine)
60 caps - SRP$57.40 120 caps - SRP$102.80 Supports mental function Phosphatidylserine is a phospholipid found in all cells, but is most concentrated in brain cells. This familiarly-called “brain nutrient” supports cognitive function, emotional well-being and behavioral performance by restoring cell membrane composition. It has also been shown to support memory. In a double blind placebo controlled multicenter study of 425 individuals, daily supplementation of phosphatidylserine over six months resulted in statistically significant support of behavioral and cognitive parameters. In another six-month study of 40 individuals, phosphatidylserine supplementation enhanced cerebral metabolism and outcomes of cognitive training. These findings are consistent with earlier studies. In a placebo- controlled investigation of 149 subjects, the group receiving phosphatidylserine scored higher than placebo in performance tests related to memory tasks of daily life. In a trial of 35 subjects, those receiving phosphatidylserine exhibited behavioral support after six months. Pure Encapsulations unique formula contains 95-98% phosphatidylserine, the highest concentration available. Consumption of Phosphatidylserine may reduce the risk of dementia in the elderly. † each vegetable capsule contains:
3 capsules per day, in divided doses, with meals.
*A healthy start for immune balance and skin health; Developed especially for mother and baby In a two year, double-blind, randomized, placebo-controlled trial at Wilhelmina Children’s Hospital, in Utrecht,
the Netherlands, 3 grams of Ecologic® PANDA, a specially designed multi-species probiotic formulation, was
administered prenatally to over 100 mothers (starting at 34 weeks) and then to their children for 12 months. is a multi-species probiotic product designed and produced by Winclove Bio Industries, BV in Amsterdam, the Netherlands. Supplement Facts Infant Dose (Bottle Fed): As a dietary supplement, dissolve
the contents of 1 sachet in breast milk or formula through age 12 months. Children 12–24 months may continue with 1
sachet dissolved in water, juice or milk, preferably between meals. Infant Dose (Breast Fed): Mother takes product according to recommendations for pregnant women.
This product
does not require refrigeration.
PureBears chewable tablet
(natural apple flavor) 90 chewable tablets - SRP $17.70 90 chewable tablets with iron - SRP $20.40
two tablets contain:
Ages
2 to 3, take 1 tablet per day, with a meal. two tablets contain:
WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of the reach of children. In case of accidental overdose, call a doctor or poison control center immediately.
Formulated with Steve Morris, N.D., A.H.GThis formula offers advanced antioxidant and adaptogen support for maintaining cell health and protecting healthy tissue. Antioxidant vitamins and minerals promote healthy cell function and cell longevity, as indicated in numerous trials involving over 8,500 individuals. Adaptogens are important for physiological and cellular homeostasis and have positive effects on immune function, the body¹s natural inflammatory response, and oxidative stress. This product was designed to:
Supplement Facts 2-4 capsules daily, with meals. four vegetable capsules contain:
Not to be taken by pregnant or lactating women.
PureDefense w/NAC 120 VCaps - SRP $45.90
*Enhances first-line immune defense and upper respiratory support Natural killer cells are part of the body’s innate, or first-line, immune response. They respond more quickly than the adaptive immune system comprised of B cells and T cells. Once activated, natural killer cell activity peaks in as quickly as several hours, providing rapid support and wide-range immune defense. EpiCor® is a fermentate of Saccharomyces cerevisiae containing various bioactive metabolites. These nutrient metabolites are produced in a specialized fermentation process and enhance immune cell production. In one cellular study, EpiCor® promoted natural killer cell activation, as well as that of B cells and T cells. In two randomized, double blind, placebo-controlled trials, EpiCor® provided statistically significant support for upper respiratory tract health and overall immune health. A separate open label, in-house trial indicated a strong potential for EpiCor® supplementation to enhance secretory IgA levels after 30 days. These various actions demonstrate the ability of EpiCor® to address both innate and adaptive immune responses. NAC (n-acetyl-l-cysteine) promotes endogenous glutathione production for antioxidant protection and provides lung defense mechanisms for healthy respiratory function. In a randomized double blind trial involving mostly older individuals, NAC supported respiratory health through the winter months. Quercetin and elderberry provide flavonoids that offer additional support for immune and respiratory function while vitamin C, vitamin D and zinc play important roles in immune cell activation. PureDefense w/NAC supports overall immune defense and provides enhanced support for upper respiratory health. Supplement Facts 2
capsules, twice per day, with meals.
PureDefense Kids 120 VCaps - SRP $28.90
*First-line immune defense for children √ For children ages 2 and up Supplement
Facts Ages
2 to 3, take 1–2 tablets per day, with or between meals.
*Whole food based multivitamin/mineral complex Indications:
Supplement
Facts 4–6 capsules per day, in
divided doses, with meals Six
vegetable capsules contain:
680g Vanilla Bean flavor - SRP $43.90 540g with stevia (Vanilla Bean flavor) - SRP $43.90 *Vegetarian protein, vitamins, minerals, omega-3 fatty acids and superfruit antioxidants for healthy weight management PureLean® Protein Blend Supplement Facts
serving size: PureLean® with Stevia Supplement Facts
serving size:
Powdered blend of soluble and insoluble fibers to promote weight management as part of a healthy lifestyle with a reduced calorie diet and regular exercise Each serving of PureLean® Fiber provides a minimum of 6 grams fiber, typically providing 3.5 grams soluble fiber from glucomannan, guar gum, apple pectin and prune fiber and 3 grams insoluble fiber from rice bran, cellulose and flaxseed. Soluble fiber helps slow the rate of digestion, promoting satiety, digestive health, nutrient absorption and healthy glycemic control. It enhances satiety by absorbing water and adding bulk in the digestive tract. Research has revealed that the high molecular weight and viscosity of glucomannan is particularly supportive. In an 8-week double blind trial, glucomannan provided statistically significant support for weight management in volunteers. Several randomized controlled trials indicate that glucomannan supports healthy lipid metabolism and promotes healthy glycemic control. Studies with glucomannan, Sunfiber® partially hydrolyzed guar gum, flaxseed and rice bran indicate that these soluble and insoluble fibers promote abdominal comfort, GI motility and bowel regularity while being well-tolerated. PureLean® Fiber provides a blend of insoluble and soluble fibers to support satiety, healthy glycemic response, and regularity. Supplement Facts 1–3 servings per day, mixed with a beverage. Adequate water intake is recommended.
Not to be taken by pregnant or lactating women.
With Metafolin® L-5-MTHF Vitamin/Mineral Distinctions: √ Provides Metafolin® L-5-methyltetrahydrofolate (L-5-MTHF), the naturally occurring, universally metabolized form of folate √ Features patented, enhanced bioactivity Chromium 454® from a proprietary Brewer’s yeast extract; supports Akt metabolic kinase activity and GLUT4 glucose transporter function* √ Introduces PureWay-C®, rapid uptake vitamin C for healthy inflammation balance, lipid antioxidant protection, and C-reactive protein metabolism* Special Features: √
Macular Synergy Complex √ Metabolic GlycoPlex √ Metabolic LipidPlex Supplement Facts 4–6
capsules per day, in divided doses, with meals.
Not to be taken by pregnant or lactating women.
With
Metafolin® L-5-MTHF Indications: Supplement Facts Take
1 packet per day (7 capsules), with a meal.
Do not take if pregnant or lactating.
PureWeigh®-FM
60 caps - SRP$37.60 120 caps - SRP$63.60 Enhanced weight management support when combined with a healthy diet and exercise PureWeigh®-FM is an encapsulated supplement companion to PureWeigh® PREMEAL Beverage for synergistic support of lipid and glucose metabolism during active weight management. Banaba leaf (Lagerstroemia speciosa L.) contains a triterpenoid compound called corosolic acid and has been reported in studies to support healthy glucose metabolism. A recent phase II, double-blind, placebo-controlled multi- center trial in Japan suggested that banaba extract maintained healthy glucose metabolism and was well tolerated by volunteers. Furthermore, an independent U.S. clinical study reported healthy weight management in human volunteers supplementing with a 1% corosolic acid banaba extract. Animal studies have suggested that corosolic acid may promote healthy weight management in part by moderating adipocyte cell differentiation. The green tea extract used in PureWeigh®-FM contains a minimum of 23% epigallocatechin gallate (EGCg), which, in addition to its antioxidant power, has been shown in recent studies to enhance thermogenesis and fat oxidation. Combined with exercise, 7-KETO™ DHEA helps increase thermogenesis and basal metabolism to support healthy lean muscle mass. Taurine promotes healthy glucose, lipid and triglyceride metabolism. Taurine also stimulates the formation of taurocholate, which increases cholesterol secretion in bile and improves fat metabolism in the liver. Additionally, taurine is a powerful antioxidant, acting to reduce free radical generation in the liver, heart, pancreas and other tissues. Chromium polynicotinate (ChromeMate®) supports glucose metabolism and enzyme activation. Biotin, a water-soluble B vitamin, facilitates protein, fat and carbohydrate metabolism by acting as a coenzyme for numerous metabolic reactions. Magnesium citrate is a highly bioavailable form of magnesium and is an important mineral involved in nearly all physiological processes, including glucose metabolism. PureWeigh®-FM is designed to provide enhanced support for glucose and lipid metabolism as part of the PureWeigh® PREMEAL Beverage weight management plan. three vegetable capsules contain:
1 capsule before each meal, 3 times per day.
PureWeigh®
PREMEAL Beverage 664g French Vanilla - SRP $52.70 640g Strawberry Banana - SRP $52.70 744g Chocolate Mint - SRP $51.50 Dietary Supplement for Weight Management, Satiety, Mood-Food Responses, and Glycemic Support. Combine with PureWeigh-FM® capsules. Successful weight management must address the underlying mechanisms leading to weight gain. PureWeigh PREMEAL is a special dietary beverage for overweight individuals with challenging weight management needs. These individuals often require additional metabolic support for mood-food responses, satiety, and glucose metabolism. PureWeigh contains an advanced spectrum of nutritional ingredients scientifically researched for their health benefits affecting weight control. PureWeigh PREMEAL beverage contains specific nutritional ingredients scientifically researched for their health benefits to support weight management. It is designed to replace the excess calories and problematic foods that would otherwise contribute to weight gain and MFR eating.* PureWeigh is the only weight management beverage available with these unique nutritional features: Serotein: A protein-nutrient complex that provides exceptionally high quality protein, a favorable
amino acid profile, and inositol.* **Green Tea Polyphenols **Red Beet Extract **Milk Thistle **Taurine Nutrient 950® Multi-Vitamin and Minerals: The "nutritional cornerstone" used by thousands of physicians providing a full spectrum of advanced delivery vitamins, minerals and antioxidants.* Features include: **Nutrient 950® multi-vitamin and mineral spectrum, with enhanced levels of Magnesium, Chromium, Folic Acid, Buffered Vitamin C, Vitamin D3, and Biotin. one scoop contains:
**WARNING: Very low calorie protein diets (below 400 calories per day) may cause serious
illness or death. Do not use for weight reduction in such diets without medical supervision. Not for use by infants, children,
pregnant or nursing women.
Pycnogenol®
50mg - 30 caps - SRP$46.20 50mg - 60 caps - SRP$85.50 100mg - 30 caps - SRP$46.20 100mg - 60 caps - SRP$85.50 Pine bark extract with antioxidant properties “Pycnogenol” originally denoted all proanthocyanidin extracts, regardless of source. However, it now refers specifically to maritime pine bark. The mixture of proanthocyanidins in pine bark supports vascular endothelial integrity by stabilizing collagenous membranes. They also promote vascular function by modulating nitric oxide levels. In addition to facilitating vitamin C regeneration and preserving vitamin E, pycnogenol is a potent hydroxyl and superoxide radical scavenger. Collectively, these actions promote the health of blood vessels. Pycnogenol® contains a minimum of 65- 75% proanthocyanidins by weight. Pycnogenol® promotes vascular health and provides powerful antioxidant support. each vegetable capsule contains:
each vegetable capsule contains:
1–3 capsules per day, in divided
doses, between meals.
Q–Gel®
(Hydrosoluble™ CoQ10)
60mg - 60 soft gels - SRP $64.20 100mg - 60 soft gels - SRP $98.60 Solubilized, natural fermented Japanese trans isomer CoQ A critical factor in CoQ10 absorption is the surface area exposed to bile salts, the body's natural emulsifier. The patented Bio Solv® technology behind Hydrosoluble™ Q-Gel® produces sub micron size CoQ10, increasing its surface area and exposure to bile salts for enhanced micellization and absorption. While this form does not require proximity to lipid containing meals, it is generally believed that taking it with meals will still offer the best bioavailability. Vitamin E is added to enhance the solubility of CoQ10. each softgel capsule contains:
1–2 capsules per day, in divided doses, with meals.
Quercetin
60 caps - SRP$17.90 120 caps - SRP$31.20 Maintains histamine release and degranulation Quercetin has been shown to be one of the most
bioactive flavonoids. Also helps with seasonal allergies, when used throughout the season.
2–4 capsules per day, in divided doses, between meals.
Reduced Glutathione
60 caps - SRP$19.90 120 caps - SRP$35.80 Antioxidant for the liver Glutathione is a key component of the antioxidant system which protects the body from free radicals at the cellular level. Reduced glutathione is involved in the synthesis and repair of DNA, and enhances the antioxidant activity of vitamin C, the transport of amino acids, and the detoxification of harmful compounds. In addition, an intracellular abundance of reduced glutathione, as compared to oxidized glutathione, helps ensure healthy cell function. It is especially important for liver function. Reduced glutathione is important for cell health and liver function. each vegetable capsule contains:
1–2 capsules per day, in divided
doses, between meals.
Relora®
60 caps - SRP$20.90 180 caps - SRP$52.40 Promotes healthy cortisol and DHEA production, moderates occasional stress and promotes satiety when combined with a healthy diet and exercise Relora® is a natural, proprietary blend of Magnolia officinalis and Phellodendron amurense. This synergistic combination of extracts helps promote positive mood and moderates occasional stress, in addition to supporting satiety and healthful eating. The magnolia and phellodendron fractions may bind to key central nervous system receptors, including those for GABA and the serotonin transporter, which encourages feelings of satiety and relaxation. A pilot clinical trial reported that Relora was well tolerated and helped promote emotional well being, muscle relaxation and moderated occasional stress. A follow-up trial reported similar results, as well as indicated that supplementing with Relora may help diminish stress-related sugary snack cravings and promote healthful eating habits. An animal study further demonstrated the supplement's ability to support mood and relaxation. A recent pilot clinical trial performed in Cincinnati, Ohio, suggested that magnolia and phellodendron helped to maintain healthy cortisol and DHEA production and metabolism, which helped support healthy body-fat distribution. Relora® is a standardized blend of extracts from Phellodendron amurense and Magnolia officinalis that studies have indicated helps mediate everyday stress-related emotions, eating behavior, and muscle tension, without causing sedation. Supports central nervous system relaxation. each vegetable capsule contains:
Do not take if pregnant or lactating.
Do not take if currently taking any prescription medication or receiving medical treatment without consulting your physician.
Respiratory Support
Complex
60 caps - SRP$23.50 120 caps - SRP$41.20 Moderates immune mediators to provide comprehensive respiratory function support Healthy plasma concentrations of antioxidants, including carotenoids, vitamin C and selenium, have been associated with maintaining healthy airway and respiratory function. One recent trial indicated that serum antioxidant levels were positively associated with vital capacity and expiratory volume. Additional studies suggest that beta–carotene and vitamin C supplementation promote respiratory function after exercise. A double blind, placebo–controlled study revealed that boswellia serrata promoted healthy breathing, vital capacity, expiratory volume and flow rate. 5–LOXIN® AKBA boswellia serrata extract is a patent pending extract providing ten times as much 3–acetyl–11–keto–beta–boswellic acid (AKBA) as typical boswellia extracts. It offers powerful support for maintaining healthy 5–lipoxygenase enzyme activity, moderating the effects of immune mediators. Numerous studies have revealed that vitamin B6 supplementation promotes respiratory health, most likely by modulating prostacyclin, thromboxane and leukotriene metabolism. Flavonols from quercetin and defatted perilla seed extract maintain healthy histamine and cytokine release in mast cells. Randomized double blind, placebo–controlled crossover trials have revealed that ginkgo promotes healthy bronchial dilation while forskolin demonstrates similar potential. Another study revealed that ginkgo plays a role in T cell activity and moderates histamine release. Respiratory Support Complex is a synergistic combination designed to promote plasma antioxidant levels, moderate histamine and cytokine release, and maintain healthy thromboxane and leukotriene metabolism to enhance bronchial and respiratory function. two vegetable capsules contain:
2–4 capsules per day, in divided doses, with meals.
Resveratrol
60 caps - SRP$19.60 120 caps - SRP$33.90 Antioxidant and cardiovascular support Resveratrol is a compound often associated with the health benefits of red wine, because of its powerful antioxidant and cardioprotectant properties. It promotes cardiovascular health through its antioxidant action and its ability to promote healthy platelet function and maintain healthy arachidonic acid metabolism. Pure Encapsulations Resveratrol is derived from one of the richest known sources, Polygonum cuspidatum, an herb utilized for centuries. Resveratrol is standardized to contain 20% trans resveratrol and 10% emodin, providing enhanced cardiovascular and antioxidant support. each vegetable capsule contains:
1 capsule per day, between meals, or as directed by a health professional.
Resveratrol EXTRA
60 caps - SRP$35.50 120 caps - SRP$63.90 Contains 100 mg trans resveratrol per capsule combined with grape seed extract and red wine polyphenols Resveratrol promotes cardiovascular health, helping to maintain healthy platelet function and arachidonic acid metabolism. A recent study suggests that it may also promote overall health, metabolic function and longevity. Grape seed extract and red wine concentrate offer polyphenols, complementing the cellular and cardiovascular health benefits of this complex. One capsule of Resveratrol EXTRA contains the amount of resveratrol equivalent of an average of 66 bottles of red wine. This formula combines resveratrol with polyphenols from red wine and grape seed for healthy cellular and cardiovascular function each vegetable capsule contains:
1–2 capsules daily, with or between meals.
Rhodiola Rosea
90 caps - SRP$15.70 180 caps - SRP$27.80 Moderates occasional physical and emotional stress Rhodiola rosea, a Siberian plant also known as Golden root, has been used traditionally for hundreds of years in countries including Russia and Siberia. Identified as an adaptogen through extensive research, Rhodiola rosea has demonstrated a number of versatile properties. In particular, this includes helping to moderate the effects of occasional physical and emotional stress. Recently, a double blind cross-over study examined the effect of Rhodiola rosea on mental performance in healthy physicians. The results suggest that rhodiola may help to moderate fatigue under stressful conditions and to support short-term memory and concentration. In a separate, double blind, placebo-controlled pilot study, Rhodiola rosea provided support for physical and mental stress in students. Promoting the activity of neurotransmitters such as serotonin, norepinephrine and dopamine plays a part in this herb¹s ability to enhance cognitive functioning, memory and attention. Rhodiola rosea may also promote energy metabolism. In a university study, it enhanced physical work capacity and improved recovery time for individuals participating in high intensity exercise. In a separate study, this extract was shown to promote endurance and coordination in athletes. Animal studies indicate that this extract may also play a role in supporting healthy heart muscle function and blood flow. One proposed cardioprotective mechanism is maintaining healthy catecholamine release in the myocardium. The extract also appears to maintain healthy adrenal catecholamine activity during stress. Furthermore, Rhodiola rosea has demonstrated the potential to support liver function, glucose and insulin metabolism, and antioxidant and cellular protection. Rhodiola may be contraindicated for individuals taking adrenergic-blocking and antiarrhythmic medications. Pure Encapsulations Rhodiola Rosea is standardized to contain 3% total rosavins and a minimum of 1% salidrosides, providing broad-spectrum adaptogen support for occasional mental and physical stress, cardiovascular and metabolic function, and cellular health. each vegetable capsule contains:
1–2 capsules per day, in divided doses, between meals.
Enhanced Support: d-Ribose
Supplement Facts 3–6 capsules per day, in divided doses, with meals.
Ribose
100g - SRP$34.10 250g - SRP$79.50 Rapid energy repletion for intense exercise Over 150 studies demonstrate the ability of ribose, a pentose sugar found in all living cells, to increase adenosine triphosphate (ATP) levels and total adenine nucleotide (TAN) recovery, promoting skeletal and cardiac muscle energy metabolism. Ribose is the key compound used by the body to form the nucleotides AMP, ADP and ATP, which are depleted during strenuous physical activity or from lack of oxygen. Skeletal and cardiac muscle rely on these metabolites for energy, and two metabolic pathways preserve these pools. The first mechanism involves salvaging end products of AMP breakdown, or preventing them from leaving the cell. If they are salvaged, they may be recycled back to AMP and ultimately to ATP. The second mechanism for preserving nucleotide pools is de novo synthesis, or formation of new nucleotides from ribose. Both of these crucial activities can only begin when ribose is converted to 5-phosphoribosyl-1-pyrophosphate (PRPP). If ribose concentrations are not sufficient, PRPP is in low supply and muscle cells cannot adequately recharge. Although the body has the ability to manufacture ribose from glucose, it is a slow process which requires glucose-6-phosphate dehydrogenase (G- 6-PDH), an enzyme typically in short supply. Supplemental ribose allows the body to bypass this step, rapidly supplying the compounds needed to boost salvage and enhance de novo synthesis. Research indicates that nucleotides decrease after repeated, intense exercise and that they may not be recovered for up to several days, leaving muscle without the ability to refuel energy stores. Ribose also offers powerful, complementary support to creatine by enhancing TAN pools, providing the necessary substrates which creatine can then convert to ATP. Ribose, taken before, during or after high-intensity exercise, accelerates replenishment of depleted adenine nucleotide pools, keeping ATP and TAN levels at their peak, and providing rapid regeneration of critical energy molecules for maximal training. each scoop (1 teaspoon) contains:
1–2 scoops per day, 30 minutes before or following an exercise session, or in divided
doses before and after exercise. On days with no exercise scheduled, take in the evening before bedtime. |
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